TABLE 5.

Treatment regimens and outcomes for AK

Patient no.	Therapya	Outcome	Reference
1	Propamidine isethionate, Neosporin	Toxicity	482
2	PHMBb	Successful	250
3	1% clotrimazole eye drops
	Dibromopropamidine isethionate	Recurrence	118
	Oral fluconazole, clotrimazole, PHMB	Progression to enucleation
4	Propamidine isethionate, neosporin	Treatment failure	161
	Miconazole, PNA, itraconazole	Toxicity
	PHMB	Resolution of disease
5	Miconazole, metronidazole, PNA, neomycin, ketoconazole	Residual infiltrate	186
6	Miconazole, metronidazole, propamidine, ketoconazole	Recurrence	186
7	Hexamidine	Well tolerated cure	51
8	PHMB and propamidine isethionate; steroids only after clinical improvement	Cure, long-term treatment necessary	196
9	Chlorhexidine and propamidine	Effective if used for the long term	402
10	Itraconazole, miconazole	Unresponsive	323
	Penetrating keratoplasty	Successful
11	Propamidine, neosporin, itraconazole, miconazole	Corneal perforation, keratoplasty	323
12	Propamidine, PHMB	Resolution of disease	323
13	PHMB, propamidine, PNA, chlorhexidine, PHMB	Propamidine toxicity	323
14	Chlorhexidine, PHMB, propamidine isethionate	Treatment of choice	260

^aTherapeutic agents reported for individual cases and treatment outcomes. PNA, prednisolone acetate.

^bPHMB is not licensed for therapeutic use. It is used as experimental drug.