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Mice with small or large CT-26 tumors were treated with daily intratumoral injections of either control ODN or CpG ODN. Figure shows the average tumor growth rate (mm3/day) following treatment. Small tumors treated with CpG ODN show slower tumor growth compared to other groups, which is consistent with longer survival and tumor regression, whereas higher tumor growth rate in other groups is consistent with their therapeutic outcome of no tumor regression and shorter survival.
