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. 2004 Sep;6(5):584–594. doi: 10.1593/neo.04217

Figure 2.

Figure 2

(A–C) Statistical analysis of epithelial cell nuclei, epithelial cell nuclei with condensed chromatin, and the appearance of cavities within the epithelial cells from rat offspring after in utero treatment with BPA or EE2 at estrus stage. Values are based on analysis of three sections for each uterine specimen (six from each group). Quantification was performed on the digitized images of nine systematic, randomly selected, representative fields and are reported as the mean ± SD. (A) Number of epithelial cell nuclei: Co, control group, 18.0 ± 4.0, n = 6; EE2, 0.2 mg/kg per day 17α-ethinyl estradiol group, 33.5 ± 12.78, n = 6; BPA0.1, 0.1 mg/kg per day BPA, 30.5 ± 6.8, n = 6; BPA50, 50 mg/kg per day BPA, 33.8 ± 3.7, n = 6. (B) Number of epithelial cell nuclei with condensed chromatin: Co, control group, 8.5 ± 3.9, n = 6; EE2, 0.2 mg/kg per day 17 α-ethinyl estradiol group, 20.0 ± 12.4, n = 6; BPA0.1, 0.1 mg/kg per day BPA, 22.7 + 6.1, n = 6; BPA50, 50 mg/kg per day BPA, 26.2 ± 7.6, n = 6. (C) Appearance of cavities within the epithelial cells: Co, control group, 7.7 ± 3.2, n = 6; EE2, 0.2 mg/kg per day 17α-ethinyl estradiol group, 15.2 ± 3.9, n = 6. BPA0.1, 0.1 mg/kg per day BPA, 16.2 ± 2.3, n = 6; BPA50, 50 mg/kg per day BPA, 14.4 ± 3.4, n = 6.