Table 2.
Cell Expression of Antigenic Structures on SOJ-6 Cell Line after Geldanamycin Treatment.
| Antigen | ||||||
| Cell Surface Expression | Intracellular Expression | |||||
| Control | Geldanamycin (3 µM) | Variation* (%) | Control | Geldanamycin (3 µM) | Variation* (%) | |
| Median Fluorescence Intensity† | Median Fluorescence Intensity† | |||||
| mAbJ28 | 8.3 | 11.8 | +42 | 7.7 | 7.3 | -5 |
| mAb16D10 | 36.9 | 74.4 | +101 | 81.8 | 47.3 | -42 |
| pAbAntipeptide | 5.1 | 5.1 | 0 | 3.2 | 3.7 | -15 |
1
*Percentage of variation versus control; average of two independent experiments.
†
Median fluorescence intensity of cells stained with the respective antibodies as determined by FACScan analysis.