Table 3.
Multivariate Analysis of PINCH Expression, Sex, Age, Site, Dukes Stage, Growth Pattern, Grade of Differentiation, and Inflammatory Infiltration in Relation to Survival in Colorectal Cancer.
| Variable | Number | Cancer Death Rate Ratio | 95% CI | P |
| PINCH | ||||
| Weak | 57 | 1.0 | - | .01 |
| Strong | 79 | 2.1 | 1.16–3.37 | |
| Sex | ||||
| Male | 82 | 1.0 | - | .67 |
| Female | 54 | 0.8 | 0.53–1.48 | |
| Age (year) | ||||
| ≤ 70 | 63 | 1.0 | - | .85 |
| > 70 | 73 | 0.9 | 0.57–1.58 | |
| Tumor location | ||||
| Proximal | 54 | 1.0 | - | .18 |
| Distal | 82 | 0.7 | 0.41–1.18 | |
| Dukes stage | ||||
| A + B | 58 | 1.0 | - | < .0001 |
| C + D | 78 | 4.0 | 2.19–7.37 | |
| Growth pattern | ||||
| Expansive | 61 | 1.0 | - | .01 |
| Infiltration | 75 | 2.0 | 1.13–3.38 | |
| Differentiation | ||||
| Better | 98 | 1.0 | - | .0003 |
| Worse | 38 | 2.8 | 1.62–4.85 | |
| Inflammatory infiltration | ||||
| Weak | 119 | 1.0 | - | .89 |
| Strong | 17 | 1.1 | 0.40–2.86 | |