FIG. 7.

IFN-γ production by cells bearing TCRγδ receptors is resistant to the effects of thiol depletion. B6 mice were treated with vehicle or DEM and then challenged with bacteria. Hepatic lymphocytes expressing intracellular IFN-γ were identified by flow cytometry as described in the Fig. 3 legend, and the surface expression of NK1.1 and TCRγδ was determined. Shown are the percentages of each hepatic lymphocyte subset from the two treatment groups that expressed intracellular IFN-γ. This experiment was performed twice with similar results. The responses of NK cells from DEM-treated mice were significantly different from those of NK cells from vehicle-treated mice (P < 0.01).