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Persistence of bacteria in spleens of vaccinated mice. Mice were vaccinated by oral (horizontal stripes) or intraperitoneal (vertical stripes) inoculation of B. abortus RB51 or were nonvaccinated (solid bars). They were challenged with oral (left side) or intraperitoneal (right side) inoculation of B. abortus 2308. Results are expressed as means (error bars represent standard deviations) (n = 5). Groups with the different letters are statistically different (P < 0.05).
