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. 2003 May;71(5):2326–2330. doi: 10.1128/IAI.71.5.2326-2330.2003

TABLE 3.

Effect of B. abortus RB51 at different days after oral vaccinationa

No. of days after vaccination Animal no. Stimulation index CFU/ spleen Spleen wt (mg) Serological titer
7 1 2.6 0 98 NEGb
2 1.8 0 99 NEG
3 1.2 0 76 NEG
4 1.2 0 87 NEG
5 1.3 0 98 NEG
Mean 1.6 0 92
15 1 1.1 0 97 NEG
2 1.1 0 96 NEG
3 1.2 25 109 NEG
4 1.1 25 95 NEG
5 1.1 0 113 NEG
Mean 1.1 10 102
30 1 Not done 0 82 1:8
2 1.3 975 135 NEG
3 1.2 75 105 1:8
4 1.1 25 66 NEG
5 1.2 25 113 NEG
Mean 1.2 220 122
42 1 1.6 0 96 NEG
2 3.7 0 112 1:2
3 3.0 0 127 1:8
4 1.7 0 129 1:16
5 5.6 0 120 NEG
Mean 3.5 0 117
a

Mice were orally vaccinated and killed at different times.

b

NEG, negative.