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Production of IL-10, IL-12, and IFN-γ by human PBMC in the presence of recombinant nematode cystatins. Anti-CD3 antibody-stimulated production of IL-10 (a), IL-12 p40 (b), and IFN-γ (c) by PBMC from eight healthy donors after 48 h. (d) Spontaneous production of IL-10 in the blood of six donors after 24 h. The concentration of rCysele1, rCysele2, rOv17, and the control protein rOv33 was 0.5 μM.
