FIG. 5.
Mucosal immune responses elicited after coinjection of OVA along with BCG. BALB/c mice were immunized i.n. with 5 × 106 cells of either nonrecombinant BCG (BCG) or CTB-producing BCG (rBCG) in the presence of OVA given i.p. and were given a booster immunization 60 days later in the same way. BALF from each group of mice were collected and individually analyzed by ELISA for the presence of anti-OVA IgA antibodies. ∗, significant difference. Statistical significance was estimated by using the Mann-Whitney test (P < 0.05).