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. 2003 May;71(5):2430–2438. doi: 10.1128/IAI.71.5.2430-2438.2003

FIG. 2.

FIG. 2.

IL-9-enhanced jejunal muscle contraction and T. spiralis worm expulsion in C57BL/6 mice. Mice were infected with T. spiralis and then treated with IL-9 (100 ng/day) or sterile PBS in 1% normal serum. Mice were killed at days 7 and 14 p.i. to investigate muscle contraction and worm recovery. (a) Maximum tension generated by jejunal muscle strips taken from T. spiralis-infected mice in response to carbachol. Day 0 shows data for control noninfected mice. (b) Dose-response relationships for carbachol-induced contraction of jejunal muscle strips from IL-9 treated infected and PBS-treated infected mice on day 7 p.i. conc., concentration. (c) Worm recovery on days 7 and 14 after T. spiralis infection. Values are means and SEMs for five animals. A single asterisk indicates a value significantly higher than that in PBS-treated infected mice. A double asterisk indicates a value significantly lower than that in PBS-treated infected mice.