Skip to main content
. 2003 May;71(5):2430–2438. doi: 10.1128/IAI.71.5.2430-2438.2003

FIG. 5.

FIG. 5.

IL-9 immunoneutralization attenuates colonic muscle contraction and inhibits worm expulsion in T. muris infection. C57BL/6 or BALB/c mice vaccinated against IL-9 or treated with anti-IL-9 antibody were infected with 100 eggs of T. muris orally. Mice were killed on different days p.i. to investigate colonic muscle contraction and worm recovery. (a) Maximum tension generated by colonic muscle in C57BL/6 mice in response to 1 μM carbachol on days 11 and 17 p.i. Day 0 shows data for control noninfected mice. (b) Worm recovery on day 34 p.i. from C57BL/6 and BALB/c mice after anti-IL-9 vaccination. (c) Worm recovery from BALB/c mice after anti-IL-9 antibody (MM9A1) treatment. A single asterisk indicates a value significantly lower in IL-9- OVA-treated mice than in OVA-treated mice. A double asterisk indicates a value significantly higher than that in OVA-treated mice. Values are means and SEMs for four animals.