TABLE 1.
Cytokines produced by in vitro-stimulated spleen cellsa
| Treatment used with T. spiralis infection | Stimulation | Level (pg/ml) of:
|
|
|---|---|---|---|
| IL-4 | IL-13 | ||
| PBS | ConA | 135.5 ± 14.3 | 392.7 ± 23.5 |
| IL-9 | ConA | 313.9 ± 60.9 | 752.9 ± 95.7 |
| PBS | T. spiralis antigen | 63.9 ± 12.8 | 156 ± 18.2 |
| IL-9 | T. spiralis antigen | 138.4 ± 17.3 | 315.9 ± 56.9 |
a
C57BL/6 mice were infected with T. spiralis orally and treated i.p. with PBS or IL-9 (100 ng/daily) from the day of infection. Mice were killed on day 8 p.i., spleen cells were stimulated with ConA or T. spiralis antigen for 48 h, and the levels of IL-4 and IL-13 present in the supernatants were investigated by ELISAs. Each value represents the mean and SEMs for four mice.