FIG. 1.

Dose-dependent (A) and time-dependent (B) leukocyte responses to SEB. The dose-dependent effect was studied 4 h after SEB challenge, and the time-dependent effect was evaluated by using 10 μg of SEB. Differential counts of leukocytes in harvested air pouch fluids were assessed after staining with Türk's solution by using a Bürker chamber. The data are means ± standard errors of the means. An asterisk indicates that the P value is <0.05 compared with the data obtained for PBS (n = 6 to 10); a number sign indicates that the P is <0.05 compared with the data obtained for the zero-time sample (n = 6 or 7). PMNLs, polymorphonuclear leukocytes.