Representative Western blot of soluble fibrinogen products from sham controls, CLP plus irrelevant antibody (CLP), and CLP plus IFN-γ antibody (CLP + IFN-γ Ab) 24 h after surgery. Authentic fibrinogen (CON) was approximately 200 kDa in size. Densitometric analysis showed that CLP rats given IFN-γ antibody had more fibrinogen products larger than 200 kDa as well as smaller than 200 kDa than those from CLP rats given irrelevant antibody. Values are means ± SEM for sham controls (n = 6), CLP (n = 9), and CLP + IFN-γ antibody (n = 9). *, P < 0.05 compared to that for sham controls; #, P < 0.05 compared to that for CLP.