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. 2003 May;71(5):2607–2614. doi: 10.1128/IAI.71.5.2607-2614.2003

FIG.4.

FIG.4.

Kinetics of leukocyte infiltration in the lungs of rats infected with S. venezuelensis concomitant with induction of allergic airway inflammation. BAL fluid (A and B) and lung tissue (C) were obtained before (uninfected) and at 2, 7, and 12 days after a single S. venezuelensis infection (one subcutaneous inoculation of 1,500 L3 larvae). Animals were immunized with a solidified egg white implant and challenged 14 and 21 days later with aerosolized OVA (OVA/OVA) or subjected to a sham operation and challenged with saline (PBS/PBS). The last aerosol challenge coincided with S. venezuelensis infection. The total numbers of infiltrating leukocytes (A) and eosinophils (B) were evaluated in BAL fluid, and an EPO assay (C) was used to estimate the number of eosinophils in lung tissue. Each value represents the mean ± the SEM of 8 to 10 rats in each group. *, P < 0.05 compared to uninfected rats; #, P < 0.05 for PBS/PBS versus OVA/OVA rats.