FIG. 1.

Genetic and physical maps of the B. avium genes discovered by STM. (A) Sizes and arrangement of B. pertussis genes (based on data in references 25 and 54). (B) B. avium genes discovered by STM. Locations of insertion mutations that genetically define each gene are indicated by black triangles. The insertions are alphanumerically coded as in Table 2. Each gene is shaded to indicate the approximate degree of similarity to the B. pertussis gene (or region of a gene) at the amino acid sequence level, as denoted by the key. (C) Comparison of the fimA-encoded amino acid sequence of B. avium, truncated FimA of B. pertussis, and complete FimA of B. bronchiseptica (B. bronch.). Additional differences are described in the text. Homology scores (colons indicate identity; periods indicate similarity) were measured by using the PAM 250 scoring matrix in MACAW.