TABLE 1.
Quantitative mntABC transcriptional levels in S. aureus strains exposed to different divalent metal ion concentrations
| Metal ion (concn) | Mean ± SD (pmol) of mntABC transcriptional levels in:
|
Ratio | |
|---|---|---|---|
| MA2181 empty vector control (S. aureus pSPT181) | MA2004 heterodiploid [S. aureus pSPT181- PmntR::dtxR(E175K)] | ||
| Fe2+- and Mn2+-free | 38.8 ± 4.14 | 2.91 ± 0.9 | 13.3:1 |
| Fe2+ (125 μM) | 0.079 ± 0.017 | <0.0076a | >10.4:1 |
| Mn2+ (125 μM) | 0.5 ± 0.15 | 0.12 ± 0.008 | 4.2:1 |
a
Undetectable; the lower limit of detection was 0.0076 pmol.