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. 2003 May;47(5):1630–1635. doi: 10.1128/AAC.47.5.1630-1635.2003

TABLE 3.

Survival of ICRa and CBA/Jb mice after infection with S. pneumoniae 21 and 4 days of systemic exposure to BMS-284756

AVC/MIC ratio % Survival
Total Free At conclusion of therapy
3 days post-treatment
ICR CBA/J ICR CBA/J
0 0 0 0 0 0
6 1 0 0 0 0
19 4 20 70 0 10
50 10 100 100 27 100
74 15 100 100 53 100
186 37 100 100 93 100
a

Neutropenic; n = 15.

b

Nonneutropenic; n = 10.