TABLE 2.

Results of dose fractionation studies

Total dosage (mg/kg)	S. aureus density (log10 CFU/thigh ± SD) obtained with the following no. of doses:				Pa
	1	2	3	4
0.5	7.83 ± 0.80	8.79 ± 0.23	9.39 ± 0.38	ND	0.028
1	5.22 ± 1.37	6.67 ± 2.64	7.74 ± 0.22	7.40 ± 1.55	0.033
2	5.02 ± 0.66	6.04 ± 1.27	6.98 ± 1.12	ND	0.004
4	4.61 ± 1.48	NDb	ND	5.83 ± 1.98	0.35
16	3.46 ± 0.42	ND	ND	4.02 ± 0.43	0.16

^aBy analysis of variance.

^bND, not determined.