Figure 3. Glucose tolerance test in wild-type (□) and PDHK4^−/− mice (■).

Glucose (2 g/kg of body mass) was administrated to overnight-fasted mice by intraperitoneal injection. All data points are means±S.E.M. with n=12 in each group. Insulin values, measured 30 min after glucose injection, are means±S.E.M. with n=6 in each group. *Significantly different between wild-type (PDHK4^+/+) and PDHK4^−/− mice (P<0.01).