Table 2.
Effects of GlcNH2·HCl on tumor growth and immune function in Sarcoma 180 tumor-bearing mice
| Group | Dose ((mg/kg)·d) | Tumor weight (g) | Inhibition ratio (%) | Thymus index (mg/g) | Spleen index (mg/g) | Lymphocyte transformation (OD570) |
| Normal control | – | – | – | 3.13±0.81 | 5.67±1.58 | 0.16±0.04 |
| Tumor control | – | 0.97±0.41 | – | 2.87±0.39 | 9.51±2.13 | 0.13±0.04 |
| GlcNH2·HCl | 125×10 | 0.70±0.46* | 27.84 | 3.11±0.54* | 9.65±2.31 | 0.16±0.11 |
| 250×10 | 0.64±0.15* | 34.02 | 3.21±1.01* | 9.89±1.01* | 0.17±0.03* | |
| 500×10 | 0.69±0.38* | 29.33 | 3.14±1.00* | 10.44±1.70* | 0.20±0.05* |
*
P<0.05 vs tumor control