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MAPK signaling pathway genes are induced to a greater extent by R5 envelopes than by X4 envelopes. The aggregate number of genes in each of the three main MAPK signaling pathways [p38, stress-activated protein kinase (SAPK)/c-Jun N-terminal kinase (JNK), and ERK/MAPK] that were modulated by R5 and X4 envelopes are shown. See Table 2 for additional information.
