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The increase in GFAP protein is delayed in IL-1R1-null mutant mice vs WT mice after a penetrating brain injury. GFAP levels were measured from lesioned neocortices by two-site ELISA at 3, 5 and 7 d after injury in wild-type or IL-1R1-null mice. Values represent the means ± S.E.M. from at least 6 mice per time point. p < 0.05 by Student t test.
