Figure 1.

Clustered image map (CIM) relating drug activity to gene expression in lung cancer cell lines – Experiment 1. (A) using filter array, (B) using GeneChip. The cluster trees of drugs (y axis) and gene expression (x axis) were shown in the CIM. Each block of colors represents correlations between clusters of genes and drugs; red (high positive correlation) and blue (negative correlation). In this analysis, gemcitabine belonged to an isolated cluster (Fig. 1A,B). GEM; gemcitabine, PAC; paclitaxel, DOC; docetaxel, VIN; vinorelbine