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Taxol biosynthesis pathway. GGPPS: Genranylgenranyl diphosphate synthase; TS: taxadiene synthase; TYHa: taxadiene 5α-hydroxylase; TAT: taxa-4(20), 11(12)-dien-5a-ol-O-acetyltransferase; TYHb: taxane 10β-hydroxylase; TBT: taxane 2a-O-benzoyltransferase; DBAT: 10-deacetyl baccatin III-O-acetyltransferase. PAM: phenyalanine aminomutase. Multiple arrows indicate several as of yet undefined steps. Red text indicates a cytochrome P450 enzyme.
