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. 2002 Feb;40(2):351–358. doi: 10.1128/JCM.40.2.351-358.2002

TABLE 1.

Patient characteristics and transplantation procedure in patients with PTLDa

Patient no. Age (yr) Disease Donor Immunosuppression Day of engraftment Antiviral treatment for prophylaxis or preemptive CMV therapy
1 26 SAA MUD ATG, CsA, MMF, prednisolone 17 days 0-30 ACV; from day 25, FC, GCV, GCV + FC
2 40 MDS MFD TGM, CsA 9 days 0-30 ACV; from day 30, GCV, GCV + FC
3 48 CML 2AgMM-FDb None 14 days 0-30 ACV; from day 14, FC, GCV, GCV + FC
4 34 ALL MUD ATG, CsA, MMF, prednisolone 12 days 0-30 ACV; from day 52, FC, FC + GCV, cidofovir
5 24 ALL MUD ATG, CsA 11 days 0-30 ACV
6 31 ALL MUD ATG, CsA, MMF, prednisolone 11 days 0-30 ACV, from day 34, GCV, FC
7 34 AML MUD ATG, CsA, MMF, prednisolone 11 days 0-30 ACV
8 37 AML 1AgMM-DUb ATG, CsA, OKT3 10c days 0-30 ACV
9 54 MM MUD ATG, CsA, OKT3 28 days 0-30 ACV, from day 19, GCV
a

Abbreviations: SAA, severe aplastic anemia; MDS, myelodysplastic syndrome; CML, chronic myeloid leukemia; ALL, acute lymphoblastic leukemia; AML, acute myeloid leukemia; MM, multiple myeloma; MUD, matched unrelated donor; 2AgMM-FD, family donor with two antigen mismatches; 1AgMM-DU, unrelated donor with one antigen mismatch; ATG, antithymocyte globulin; CsA, cyclosporine; MMF, mycofenolate mofetil; ACV, acyclovir; FC, foscarnet; GCV, ganciclovir.

b

Both patients received T-cell-depleted grafts.

c

Primary graft failure with a second graft at day 34; engraftment was at day 10 after the second transplantation.