Table 4.
GO functional terms for B. anynana genes annotated to Drosophila CG numbers
GO TERMS | # | % | P-value |
Molecular function | |||
Signal transducer activity (GO: 0004871) | 72 | 7 | 0.3025 |
Structural molecule activity (GO: 0005198) | 195 | 25 | |
Motor activity (GO: 0003774) | 15 | 16 | |
Catalytic activity (GO: 0003824) | 568 | 14 | |
Transporter activity (GO: 0005215) | 151 | 12 | 0.3294 |
Binding (GO: 0005488) | 651 | 15 | |
Antioxidant activity (GO: 0016209) | 13 | 33 | |
Enzyme regulator activity (GO: 0030528) | 52 | 14 | |
Transcription regulator activity (GO: 0030528) | 103 | 12 | 0.0011 |
Transcription factor activity (GO: 0003700) | 28 | 7 | |
Translation regulator activity (GO: 0045182) | 26 | 28 | |
Biological process | |||
Development (GO: 0007275) | 190 | 8 | |
Larval or pupal development (GO: 0002165) | 57 | 10 | |
Pattern specification (GO: 0007389) | 37 | 10 | |
Metamorphosis (GO: 0007552) | 43 | 9 | |
Aging (GO: 0007568) | 5 | 10 | |
Pigmentation (GO: 0048066) | 4 | 7 | |
Regulation of development (GO: 0050793) | 5 | 7 | |
Morphogenesis (GO: 0009653) | 89 | 9 | 0.1183 |
Embryonic development (GO: 0009790) | 46 | 9 | |
Physiological process (GO: 0007582) | 1013 | 13 | |
Behavior (GO: 0007610) | 31 | 8 | |
Cellular process (GO: 0009987) | 1000 | 13 | |
Regulation of biological process (GO: 0050789) | 217 | 13 | |
Highlights | |||
Structural constituent of ribosome (GO: 0003735) | 110 | 57 | |
Tubulin (GO: 0045298) | 4 | 25 | |
Wing disc development (GO: 0035220) | 21 | 11 | |
Tracheal system development (GO: 0007424) | 13 | 10 | |
Wnt receptor signaling pathway (GO: 0016055) | 11 | 15 | |
sevenless signaling pathway (GO: 0045500) | 2 | 22 | |
Notch signaling pathway (GO: 0007219) | 3 | 7 | |
frizzled signaling pathway (GO: 0007222) | 6 | 29 | |
Eye pigment metabolism (GO: 0042441) | 4 | 13 |
# is the number of B. anynana gene annotations obtained via BLAST analysis D. melanogaster and B. mori (total CG numbers in B. anynana with GO annotation = 1,164) that belong to the listed GO categories. % refers to the proportion of D. melanogaster genes (total CG numbers in D. melanogaster with GO annotation = 10,391) found in B. anynana for each GO category. The categories specified in this list are a limited subset of all GO categories found to be represented [see complete list in Additional file 7]. A Chi-square test was performed for the null hypothesis that the fraction of B. anynana UniGenes in each GO category relative to the total number of B. anynana UniGenes with an assigned category is equivalent to the fraction of D. melanogaster genes in that category relative to all D. melanogaster genes with a GO assignment. For the cases where Chi-square p > 0.0001, p-values are provided. All other cases are p < 0.0001.