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functional categories. Genes differentially expressed at 37°C and 28°C, grouped by functional classification according to the NCBI L. interrogans 56601 COGs database http://www.ncbi.nlm.nih.gov. Genes were regarded as differentially expressed when the expression levels differed by at least twofold. The number of upregulated (red bars) and downregulated (blue bars) genes in each functional group is shown.
