Table 1.
Summary of immunological parameters of HIV patients and HIV-seronegative individuals for the cross-sectional study.
| HIV-Rec-adults | Healthy-adults | (a)p | HIV-Rec-children | Healthy-children | (b)p | (c)p | |
| No. of subjects | 9 | 15 | 10 | 20 | |||
| T cells | |||||||
| CD4+ (%) | 33.7 (25.9; 42.3) | 42 (29.3; 56.6) | 0.035 | 30.5 (18.1; 39.98) | 42.3 (29.5; 55.4) | 0.001 | 0.193 |
| CD8+ (%) | 36.2 (25.7; 53.5) | 22.7 (16.1; 32.3) | <0.001 | 38.6 (24.1; 63.9) | 22.3 (13.6; 28.1) | <0.001 | 1 |
| CD4+/μl | 675 (563; 922) | 864 (524; 1265) | 0.815 | 837.5 (631; 1111) | 1288 (588; 2804) | 0.016 | 0.072 |
| CD8+/μl | 881 (632; 1765) | 492 (196; 878) | <0.001 | 1038.5 (444; 2726) | 673 (304; 1641) | 0.091 | 0.620 |
| Thymic function | |||||||
| TRECs/105 PBMC | 25 (10; 106) | 247 (10; 865) | 0.006 | 10186 (1430; 18026) | 16097 (5944; 43620) | 0.082 | <0.001 |
| IL-7 (pg/ml) | 5.5 (2.9; 11.2) | 4.3 (2.4; 7.5) | 0.015 | 2.2 (0.8; 7.14) | 0.6 (0.3; 1.8) | 0.001 | 0.002 |
Values are expressed as median (minimum; maximum). TREC: TCR rearrangement excision circles. Differences were calculated by U-test of Mann-Whitney.
(a): p-values between HIV-Rec-adults and Healthy-adults.
(b): p-values between HIV-Rec-children and Healthy-children.
(c): p-values between HIV-Rec-adults and HIV-Rec-children.