Fig. 1. Analysis of MTJ1 amino acid sequence (Swiss Protein Data Base accession number Q61712).
The transmembrane domains (long dashed underline) were predicted by using the TMPRED program. The signal peptide (dotted line) and cleavage site (arrow) were predicted with the program SignalP v1.1 (85). The DnaJ-like domain (triple underline) and the SANT domains (bold plain underline) were predicted by using the SMART program (86). The second region that presents homology with the yeast Sec63p (small dashed underline) has been identified using the alignment program SIM. The C-terminal endoplasmic reticulum retrieval signal (thick dotted line) was identified with the program PSORT II.