Figure 2.

CD8⁺ cell suppression of HIV-1_SF33 virus replication in acutely infected CD4⁺ cells. The percent suppression of virus replication at a CD8⁺:CD4⁺ cell ratio of 2:1 is presented for 24 HIV⁺, 35 EU, and 20 unexposed (control) subjects. Statistical significance was determined by comparing the actual suppression values of all EU vs. unexposed individuals using a nonparametric Mann–Whitney analysis (P < 0.0016). A cutoff value of >45% suppression used to distinguish the EU population is shown by a dashed line.