Figure 3.

Posttranslational modification levels of type I collagen in BS bone normalized against normal bone. Bar graph shows that (glycosylated) Hyl levels of the triple helix are normal, which is in contrast to that of the telopeptides, where hardly any Hyl is seen. The lack of telopeptide Hyl-derived crosslinks is compensated by increased levels of crosslinks derived from the telopeptide Lys route. HLNL (Lys), hydroxylysinonorleucine derived from telopeptidyl lysine; HLNL (Hyl), hydroxylysinonorleucine derived from telopeptidyl Hyl.