Figure 2.

Acute administration of corticosterone enhances skin DTH. A time course of changes in the thickness of right pinnae of previously sensitized animals challenged with DNFB is shown. Corticosterone (CORT, 5 mg/kg) was administered i.p. to ADX animals (A) or through drinking water (100 or 400 μg/ml) to intact animals (B). Control animals were treated with vehicle: 30% HBC (A) or 0.6% ethanol (B). Corticosterone-treated animals showed a significantly larger DTH response than vehicle-treated animals. (∗, P < 0.05, independent t test.)