Figure 6.

Acute administration of stress hormones increases the cellularity of cervical lymph nodes that drain the site of the skin DTH reaction. Epinephrine (EPI, 0.5 mg/kg), corticosterone (CORT, 5 mg/kg), or epinephrine plus corticosterone (EPI+CORT, 0.5 mg/kg plus 5 mg/kg, respectively) were administered to ADX animals. Control animals were treated with vehicle (VEH, 30% HBC). Lymph nodes were collected, and lymphocytes were isolated 48 h after the induction of DTH. Compared with vehicle-treated animals, hormone-treated animals showed higher T lymphocyte numbers in cervical lymph nodes that drain the site of the DTH reaction. (∗, P < 0.05, independent t test.)