Table 3.
Amino acid empirical contact energies
| CYS | MET | PHE | ILE | LEU | VAL | TRP | TYR | ALA | GLY | |
| CYS | -3.477 | -2.240 | -2.424 | -2.410 | -2.343 | -2.258 | -2.080 | -1.892 | -1.700 | -1.101 |
| MET | -2.240 | -1.901 | -2.304 | -2.286 | -2.208 | -2.079 | -2.090 | -1.834 | -1.517 | -0.897 |
| PHE | -2.424 | -2.304 | -2.467 | -2.530 | -2.491 | -2.391 | -2.286 | -1.963 | -1.750 | -1.034 |
| ILE | -2.410 | -2.286 | -2.530 | -2.691 | -2.647 | -2.568 | -2.303 | -1.998 | -1.872 | -0.885 |
| LEU | -2.343 | -2.208 | -2.491 | -2.647 | -2.501 | -2.447 | -2.222 | -1.919 | -1.728 | -0.767 |
| VAL | -2.258 | -2.079 | -2.391 | -2.568 | -2.447 | -2.385 | -2.097 | -1.790 | -1.731 | -0.756 |
| TRP | -2.080 | -2.090 | -2.286 | -2.303 | -2.222 | -2.097 | -1.867 | -1.834 | -1.565 | -1.142 |
| TYR | -1.892 | -1.834 | -1.963 | -1.998 | -1.919 | -1.790 | -1.834 | -1.335 | -1.318 | -0.818 |
| ALA | -1.700 | -1.517 | -1.750 | -1.872 | -1.728 | -1.731 | -1.565 | -1.318 | -1.119 | -0.290 |
| GLY | -1.101 | -0.897 | -1.034 | -0.885 | -0.767 | -0.756 | -1.142 | -0.818 | -0.290 | 0.219 |
| THR | -1.243 | -0.999 | -1.237 | -1.360 | -1.202 | -1.240 | -1.077 | -0.892 | -0.717 | -0.311 |
| SER | -1.306 | -0.893 | -1.178 | -1.037 | -0.959 | -0.933 | -1.145 | -0.859 | -0.607 | -0.261 |
| ASN | -0.788 | -0.658 | -0.790 | -0.669 | -0.524 | -0.673 | -0.884 | -0.670 | -0.371 | -0.230 |
| GLN | -0.835 | -0.720 | -0.807 | -0.778 | -0.729 | -0.642 | -0.997 | -0.687 | -0.323 | 0.033 |
| ASP | -0.616 | -0.409 | -0.482 | -0.402 | -0.291 | -0.298 | -0.613 | -0.631 | -0.235 | -0.097 |
| GLU | -0.179 | -0.209 | -0.419 | -0.439 | -0.366 | -0.335 | -0.624 | -0.453 | -0.039 | 0.443 |
| HIS | -1.499 | -1.252 | -1.330 | -1.234 | -1.176 | -1.118 | -1.383 | -1.222 | -0.646 | -0.325 |
| ARG | -0.771 | -0.611 | -0.805 | -0.854 | -0.758 | -0.664 | -0.912 | -0.745 | -0.327 | -0.050 |
| LYS | -0.112 | -0.146 | -0.270 | -0.253 | -0.222 | -0.200 | -0.391 | -0.349 | 0.196 | 0.589 |
| PRO | -1.196 | -0.788 | -1.076 | -0.991 | -0.771 | -0.886 | -1.278 | -1.067 | -0.374 | -0.042 |
| THR | SER | ASN | GLN | ASP | GLU | HIS | ARG | LYS | PRO | |
| CYS | -1.243 | -1.306 | -0.788 | -0.835 | -0.616 | -0.179 | -1.499 | -0.771 | -0.112 | -1.196 |
| MET | -0.999 | -0.893 | -0.658 | -0.720 | -0.409 | -0.209 | -1.252 | -0.611 | -0.146 | -0.788 |
| PHE | -1.237 | -1.178 | -0.790 | -0.807 | -0.482 | -0.419 | -1.330 | -0.805 | -0.270 | -1.076 |
| ILE | -1.360 | -1.037 | -0.669 | -0.778 | -0.402 | -0.439 | -1.234 | -0.854 | -0.253 | -0.991 |
| LEU | -1.202 | -0.959 | -0.524 | -0.729 | -0.291 | -0.366 | -1.176 | -0.758 | -0.222 | -0.771 |
| VAL | -1.240 | -0.933 | -0.673 | -0.642 | -0.298 | -0.335 | -1.118 | -0.664 | -0.200 | -0.886 |
| TRP | -1.077 | -1.145 | -0.884 | -0.997 | -0.613 | -0.624 | -1.383 | -0.912 | -0.391 | -1.278 |
| TYR | -0.892 | -0.859 | -0.670 | -0.687 | -0.631 | -0.453 | -1.222 | -0.745 | -0.349 | -1.067 |
| ALA | -0.717 | -0.607 | -0.371 | -0.323 | -0.235 | -0.039 | -0.646 | -0.327 | 0.196 | -0.374 |
| GLY | -0.311 | -0.261 | -0.230 | 0.033 | -0.097 | 0.443 | -0.325 | -0.050 | 0.589 | -0.042 |
| THR | -0.617 | -0.548 | -0.463 | -0.342 | -0.382 | -0.192 | -0.720 | -0.247 | 0.155 | -0.222 |
| SER | -0.548 | -0.519 | -0.423 | -0.260 | -0.521 | -0.161 | -0.639 | -0.264 | 0.223 | -0.199 |
| ASN | -0.463 | -0.423 | -0.367 | -0.253 | -0.344 | 0.160 | -0.455 | -0.114 | 0.271 | -0.018 |
| GLN | -0.342 | -0.260 | -0.253 | 0.054 | 0.022 | 0.179 | -0.290 | -0.042 | 0.334 | -0.035 |
| ASP | -0.382 | -0.521 | -0.344 | 0.022 | 0.179 | 0.634 | -0.664 | -0.584 | -0.176 | 0.189 |
| GLU | -0.192 | -0.161 | 0.160 | 0.179 | 0.634 | 0.933 | -0.324 | -0.374 | -0.057 | 0.257 |
| HIS | -0.720 | -0.639 | -0.455 | -0.290 | -0.664 | -0.324 | -1.078 | -0.307 | 0.388 | -0.346 |
| ARG | -0.247 | -0.264 | -0.114 | -0.042 | -0.584 | -0.374 | -0.307 | 0.200 | 0.815 | -0.023 |
| LYS | 0.155 | 0.223 | 0.271 | 0.334 | -0.176 | -0.057 | 0.388 | 0.815 | 1.339 | 0.661 |
| PRO | -0.222 | -0.199 | -0.018 | -0.035 | 0.189 | 0.257 | -0.346 | -0.023 | 0.661 | 0.129 |
Contact energies are reported for all amino acid pairs corresponding to the SC+CA contact definition and employing a cutoff of 1.0 Å.