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. 2003 Mar 23;4:11. doi: 10.1186/1471-2164-4-11

Table 3.

Parameter estimates for the total data set consisting of 10759 genes and for the "conservative set" of 2721 genes.

Parameter Type of effect1 Estimate Total set Estimate Conserved set
μ Fixed 10.56 12.18
C (cell line 2; U2OS) Fixed 0.086 -0.028
D (Cy3) Fixed -0.026 -0.022
P (non-amplified) Fixed -0.74 -1.14
CP22 (cell line 2 and non-amplified) Fixed -0.0043 0.0089
σA (array) Random 0.28 0.30
σB (batch) Random 0.041 0.041
σC (gene) Random 1.36 0.98
σAD Random 0.039 0.040
σGP Random 0.85 0.79
σCG Random 0.74 0.54
σAG Random 0.44 0.44
σDG Random 0.048 0.050
σCGP Random 0.22 0.028
σε Random 0.22 0.22

Annotations: μ = overall mean signal intensity, C = cell line type, D = labeled dye, P = protocol. 1 Of the fixed effects, C, D, and P have two levels while CP is an interaction between two fixed effects. The random effects were modeled as independently normally distributed random effects with zero mean and constant standard deviation. σCGP is the cell line specific GP effect and is the effect of primary interest.