Figure 4.
Effect of calmidazolium on the changes in tone produced by l-NA and by ACh. (A) Effect of 1 μM calmidazolium on the tone of PGF2α-contracted rabbit aortic rings before (open bars) and after (hatched bars) the application of 100 mM l-NA. Data are presented as the mean ± SEM of eight separate experiments. ∗, P < 0.05. (B) Effect of 1 μM calmidazolium on the relaxant response of 1 μM phenylephrine-contracted aortic rings to 1 μM ACh. Data are presented as the mean ± SEM of eight separate experiments. ∗∗∗, P < 0.001.