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. 1999 Feb 2;96(3):1123–1128. doi: 10.1073/pnas.96.3.1123

Figure 6.

Figure 6

Effect of tyrosine kinase inhibitors on the l-NA-induced increase in tone of rabbit aortic rings. Rabbit aortic rings were precontracted to ≈25% of the maximal phenylephrine-induced tone with PGF2α (open bars). Once a stable contraction had been achieved, 100 μM l-NA was applied (hatched bars). Experiments were performed in the absence and presence of 30 μM erbstatin A (A), 5 μM herbimycin A (B), and 100 μM genistein (C). Data are presented as the mean ± SEM of seven separate experiments. ∗, P < 0.05; ∗∗, P < 0.01.