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. 2003 Apr 1;100(8):4742–4747. doi: 10.1073/pnas.0737855100

Figure 4.

Figure 4

Levels of A2PE-H2 and A2E in abcr−/− RPE after 1 month of treatment with isotretinoin. (A) Levels of A2PE-H2 in RPE from 3-month-old abcr−/− mice before treatment (green bar, n = 3 mice), 4-month-old untreated (blue bar, n = 3) or DMSO-treated (blue bar, n = 3) control mice, and 4-month-old mice treated with 40 mg/kg per day isotretinoin (red bar, n = 3). Values are expressed as peak-height milliabsorption units (mAU) at wavelength (λ) = 500 nm. (B) Levels of A2E in RPE from 3-month-old abcr−/− mice before treatment (green bar, n = 3), 4-month-old DMSO-treated control mice (blue bar, n = 3), and 4-month-old mice treated with 40 mg/kg per day isotretinoin (red bar, n = 3). Values are expressed in mAU at λ = 435 nm. Error bars show SD.