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(A and B) Inclusion of rhEPO (100 ng/ml) in the culture medium of adult rat cardiomyocytes reduced cell apoptosis in the presence of acidosis. (C and D) In contrast, the presence of rhEPO did not reduce necrosis, which was a smaller component of cell death. EMB, ethidium monoazide bromide; TdT, terminal deoxynucleotidyltransferase; N, normoxia; H, hypoxia. Results are means ± SD; n = 5 or 6 in each determination. *, P < 0.05 vs. N or N + EPO; †, P < 0.05 vs. H.
