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Fibrillization (Thio T fluorescence assay) of the three α-synuclein variants, WT, A53T, and A30P (200 μM), and relevant A53T/WT and A30P/WT equimolar mixtures (200 μM total protein). (A) Fibrillization of (left to right) A53T (red), 1:1 A53T/WT (pink), and WT (white). (B) Fibrillization of (left to right) WT (white), 1:1 A30P/WT (light green), and A30P (green). Note expanded y axis relative to A (identical WT run is plotted in both A and B).
