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. 2003 Mar 15;111(6):915–924. doi: 10.1172/JCI16156

Figure 2.

Figure 2

Histological assessment of acute inflammatory arthritis in C57BL/6 and IFN-γ–/– mice. Acute inflammatory arthritis was induced by intra-articular injection of 200 μg mBSA into the knee joint followed by three daily subcutaneous injections of 250 ng IL-1β. Mice were sacrificed on day 7 following mBSA injection. H&E-stained joint sections were graded for five features of inflammatory arthritis, each on a scale of 0 (normal) to 5 (severe). Results shown are the mean + SEM of 16 knee joints and are representative of three independent experiments.