FIG. 1.

Acute replication of virus in the genital tract. Groups of B7KO and BALB/c mice were inoculated i.vag. with HSV-2 G-6 at a dose of 500 or 5,000 PFU. Vaginal vaults were swabbed twice with calcium alginate swabs on days 1 through 4 postinoculation. Virus titer in swab samples was determined by standard plaque assay. Data from two experiments were pooled. Values represent the geometric mean titer ± standard errors of the means for 16 mice per group.