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Survival of B7KO mice and BALB/c mice after HSV-2 infection
| Dose (PFU) | Group | Proportion of mice surviving (no. surviving/no. infected)a |
|---|---|---|
| 50b | B7KO | 8/8 |
| 50 | BALB/c | 8/8 |
| 500c | B7KO | 9/32 |
| 500 | BALB/c | 23/32 (P = 0.0005) |
| 5,000c | B7KO | 5/31 |
| 5,000 | BALB/c | 15/31 (P = 0.0066) |
Values for B7KO mice were compared with values for BALB/c mice infected with the same dose of HSV-2 by the chi-square test.
Result of one experiment.
Pooled results of four experiments.
