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Sequential Fourier maps showing the time course of cleavage of the Cys-254–Cys-265 disulfide bond in TcAChE. Cysteine residues were refined as alanine residues to avoid model bias. (a) 3Fo-2Fc maps, contoured at 1.5 σ. (b) Fo-Fc maps, contoured at 3 σ.
