TABLE 3.
Distribution of β-galactosidase labeling in nonneural tissues of mice containing HSV-1 IE gene or late gene reporter transgenes
| Sample | No. of animals positivea
|
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| ICP0
|
ICP27
|
gC
|
Nontransgenic | |||||||
| Tg3180 | Tg6825 | Tg3054 | Tg3058 | Tg6818 | Tg3401 | Tg3403 | Tg3405 | |||
| Cornea | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Adrenal | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Kidney | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Liver | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Spleen | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Heart | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | |
| Lung | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Intestine | 4 | 4 | 2 | 3 | 0 | 0 | 0 | 0 | 0 | |
Each number represents the number of mice out of four which contained β-galactosidase-labeled cells in the indicated nonneural tissues. The labeled cells in the outer muscle layers of the intestinal wall were myenteric plexus neurons.