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. 2003 Apr;41(4):1594–1599. doi: 10.1128/JCM.41.4.1594-1599.2003

TABLE 1.

Resistance-associated mutations in HIV-1 PR and RT present in test samples

Isolate or patient Source Resistance-associated mutation(s)a
Plasma HIV-1 RNA level (copies/ml)
PR RT
VA-MH-001 Plasma 63P None 353,900
VA-MH-003 Plasma None 184V 2,618
VA-MH-004 Plasma None 67N, 70R, 103N, 184V, 219Q 1,279
VA-MH-007 Plasma 36I None 28,881
VA-MH-009 Plasma 10I, 63P 103N, 184V, 215F 43,525
018-027-001 Plasma 30N, 36I, 63P 67N, 103N 10,259
018-027-002 Plasma 35D, 46L, 63P 118I 212,343
018-027-003 Plasma 10F, 30N, 63P, 88D 41L, 118I, 184V, 215Y 20,722
018-027-004 Plasma 63P 103N 156,790
018-027-005 Plasma 63P 41L, 44D, 67N, 69D, 118I, 210W, 215D/Y 13,451
018-027-006 Plasma 10I None 118,334
018-027-007 Plasma 10I, 54V, 63P, 84V 41L, 74V, 103N, 106A, 108I, 181C, 190A, 210W, 215N/S/Y 2,535,030
018-027-008 Plasma 63P None 6,288
018-027-009 Plasma 10I, 36I, 46I, 48V, 82A 41L, 62V, 75T, 106I, 118I, 181C, 184V, 188L, 215F 526,314
018-027-010 Plasma 10I, 36I, 54V, 63P, 71V, 82A, 84V, 90M 41L, 44D, 67N, 69D, 103N, 108I, 184V, 210W, 215Y 31,797
PE-009-028c IMC 20R, 63P, 77I, 90M 181C, 184V, 215N/S/Y NAb
13-021-027 IMC 30N, 90M 181C, 215Y NA
a

Notation designates codon and altered amino acid residue within HIV-1 PR and RT.

b

NA, not applicable.

c

Sample PE-009-028 was a 1:1 mixture of wild-type and mutant IMC.