Table 1.

Genotype findings at all loci tested. Functional variations were observed in the TLR 5 gene, the flagellin receptor, TLR5-F616L, a heterozygous mutation TLR5-R392 and two coagulation variations resulting in thrombotic events (HT TF603 and PAI-1 4G-4G homozygous). Genes encoding proteins involved in inflammation genes were normal.

	Ref	WT/WT	WT/M	M/M			WT/WT	WT/M	M/M
TLR2 R753Q	rs5743708	X			IL 10-1082	rs1800872	X
TLR5-R392	rs5744168		X		TNF b1/b2	rs2229094	X
TLR5-N592S	rs2072494	X			TNF 238	rs361525	X
TLR5-F616L	rs5744174			X	TNF 308	rs1800629	X
TLR4 D299G	rs4986790	X			TNF 376	rs1800750	X
Fc-GrIIα	rs1801274	X			PAI-1	rs1799768			X
CD 14	rs2569190		X		Fibrinogen	rs6050	X
SPD 11	rs721917	X			TF p603	[14]		X
SPD 160	rs2243639		X		EPCR	rs867186	X
MIF	rs755622		X		Factor II	rs1799963	X
IL 6	rs1800795		X		Factor V	Rs6025	X
IL 10-592	rs1800872		X		Factor VII	Rs6046	X

Abreviations : Toll like receptor (TLR); Fc receptor for IgG (Fc-gamma RII); macrophage migration inhibitory factor (MIF); Endothelial protein C receptor (EPCR); Tissue factor (TF); Tumor Necrosis Factor (TNF); Surfactant Protein D(SPD); WT: Wild type concerns the frequent allele; M: mutation concerns the rare allele. Ref: reference number for the studied SNP.