FIG. 1.

(a) Effect of disruption of lmo2754 on the invasion of the organism on C2Bbe1 cells. Numbers of L. monocytogenes cells invaded were expressed as log CFU/well. Results are representative of triplicate experiments. (b) Effect of pORI19 disruption of PBPs on the survival of EGDe in vivo. Numbers indicate the genes that were disrupted. Mice were injected intraperitoneally, and the number of bacteria recovered from the spleen was determined at 3 days postinfection. Error bars represent the standard deviations from the means (n = 5). *, mean is statistically significant with respect to the wild-type value (P < 0.05).